All About Depression by Dr Jo Borrill, Clinical Research

By Dr Jo Borrill, Clinical Research

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18. How does bipolar depression differ from major depression? The symptoms of depression in bipolar disorder are the same as in major depression. In fact the depressive episode of bipolar disorder meets the same criteria outlined for a major depressive episode in the DSMIV-TR, as described in Question 12. The differences between the illnesses have more to do with their genetics, clinical course, prognosis, and treatment. qxd 10/18/06 2:32 PM Page 44 100 QUESTIONS & ANSWERS ABOUT BIPOLAR (MANIC-DEPRESSIVE) DISORDER years for the correct diagnosis of bipolar disorder to be made in a person who presents for treatment of depression.

Serotonin is involved in mood regulation, anxiety, pain perception, appetite, sleep, sexual behavior, and impulsive behavior. Biogenic amines a group of compounds in the nervous system that participate in the regulation of brain activity, which includes dopamine, serotonin, and norepinephrine. 21 The Basics Thousands of different chemicals participate in brain function and fall into different groups based on their chemical structure, mechanism of action, psychotropic effects, or where they come from in the body.

The treatment was once vastly different, but with the advent of atypical antipsychotics, treatment options often overlap as well, so medication history is not an adequate means for determining a person’s past psychiatric diagnoses. qxd 10/18/06 2:32 PM Page 41 100 QUESTIONS & ANSWERS ABOUT BIPOLAR (MANIC-DEPRESSIVE) DISORDER • • • • • Delusions Hallucinations Disorganized speech Disorganized behavior Negative symptoms (affective flattening, alogia, avolition) Any of these symptoms can be present if psychotic during a manic episode.

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